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Cats seem to delight in peeing in the most inconvenient places like on your mattress.  The good news is that with a little patience and perseverance and some Odor Medicine O.F. Concentrate you can fix it.

Use your nose and a black light to locate the affected areas.  Saturate each spot with a strong mixture of O.F. and work it into the mattress and let it soak for about 20 minutes.  Then extract as much as you can with a wet/dry vacuum.  Let it dry for about 2 days and then evaluate the results.  If you still have odor repeat this process and you may try injecting the O.F. into the mattress with a turkey baster needle that you can purchase at a grocery store.  It is very important to extract as much of the O.F. mixture as possible in order to ensure that it dries out completely in a couple of days.  You may position a hair dryer to blow hot air on each spot to speed the process and help make sure it gets completely dry.